Hard copies of reading assignments are available in SHM L-200.
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Week 0 (9/6) Course Introduction - Ivan & Angeliki
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Week 1 (9/9, 9/13) Inhibition and Excitation in Cortical Circuits - Jess Cardin
Gentet, L. J. et al. Unique functional properties of somatostatin-expressing GABAergic neurons in mouse barrel cortex. Nat Neurosci 15, 607–612 (2012).
Kapfer, C., Glickfeld, L. L., Atallah, B. V & Scanziani, M. Supralinear increase of recurrent inhibition during sparse activity in the somatosensory cortex. Nat Neurosci 10, 743–753 (2007).
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Week 2 (9/16, 9/20) Optical Imaging of Neural Activity - Alex Kwan
Howe, M. W. & Dombeck, D. A. Rapid signalling in distinct dopaminergic axons during locomotion and reward. Nature 535, 505–510 (2016).
Makino, H. & Komiyama, T. Learning enhances the relative impact of top-down processing in the visual cortex. Nat Neurosci 18, 1116–1122 (2015).
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Week 3 (9/23, 9/27) Molecular Mechanisms of Synaptic Transmission - Susumu Tomita
Gross, G. G. et al. An E3-ligase-based method for ablating inhibitory synapses. Nat Meth 13, 673–678 (2016).
O’Sullivan, G. A. et al. Forebrain-specific loss of synaptic GABAA receptors results in altered neuronal excitability and synaptic plasticity in mice. Mol. Cell. Neurosci. 72, 101–113 (2016).
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Week 4 (9/30, 10/4) Sensory Systems: Olfaction - Charlie Greer
Huang, L. et al. Task Learning Promotes Plasticity of Interneuron Connectivity Maps in the Olfactory Bulb. J. Neurosci. 36, 8856–8871 (2016).
Sailor, K. A. et al. Persistent Structural Plasticity Optimizes Sensory Information Processing in the Olfactory Bulb. Neuron 91, 384–396 (2016).
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Week 5 (10/7, 10/11) Mechanosensation - Slav Bagriantsev
Hong, G.-S. et al. Tentonin 3/TMEM150c Confers Distinct Mechanosensitive Currents in Dorsal-Root Ganglion Neurons with Proprioceptive Function. Neuron 91, 107–118 (2016).
Woo, S.-H. et al. Piezo2 is the principal mechanotransduction channel for proprioception. Nat Neurosci 18, 1756–1762 (2015).
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Week 6 (10/14, 10/25) Neural Circuit Development - Mike Crair
Brown, A. et al. Topographic mapping from the retina to the midbrain is controlled by relative but not absolute levels of EphA receptor signaling. Cell 102, 77–88 (2000).
Cang, J. et al. Selective Disruption of One Cartesian Axis of Cortical Maps and Receptive Fields by Deficiency in Ephrin-As and Structured Activity. Neuron 57, 511–523 (2008).
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Week 7 (10/28, 11/1) Neurodegeneration - Sreeganga Chandra
Hong, S. et al. Complement and microglia mediate early synapse loss in Alzheimer mouse models. Science 352, 712–716 (2016).
Mao, X. et al. Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3. Science 353 (2016).
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Week 8 (11/4, 11/8) Neural Basis of Food Intake - Ralph DiLeone
Betley, J. N. et al. Neurons for hunger and thirst transmit a negative-valence teaching signal. Nature 521, 180–185 (2015).
Chen, Y., Lin, Y.-C., Zimmerman, C. A., Essner, R. A. & Knight, Z. A. Hunger neurons drive feeding through a sustained, positive reinforcement signal. Elife 5, e18640 (2016).
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Week 9 (11/11, 11/29) Membrane Dynamics in Neuronal Function - Pietro De Camilli
Koenig, J. H. & Ikeda, K. Disappearance and reformation of synaptic vesicle membrane upon transmitter release observed under reversible blockage of membrane retrieval. J. Neurosci. 9, 3844-3860 (1989).
Sollner, T. et al. SNAP receptors implicated in vesicle targeting and fusion. Nature 362, 318–324 (1993).
[Supplementary] Südhof, T. C. The Molecular Machinery of Neurotransmitter Release (Nobel Lecture). Angew. Chem. Int. Ed. 53, 12696–12717 (2014).
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Week 10 (12/2, 12/6) Decision Making - Ifat Levy
Kable, J. W. & Glimcher, P. W. The neural correlates of subjective value during intertemporal choice. Nat Neurosci 10, 1625–1633 (2007).
Lim, S.-L., O'Doherty, J. P. & Rangel, A. The Decision Value Computations in the vmPFC and Striatum Use a Relative Value Code That is Guided by Visual Attention. J. Neurosci. 31, 13214-13223 (2011).
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Week 11 (12/9, 12/13) Computational Psychiatry - Phil Corlett
Kaplan, C. M. et al. Estimating changing contexts in schizophrenia. Brain 139, 2082–2095 (2016).
Romaniuk, L. et al. Midbrain activation during Pavlovian conditioning and delusional symptoms in schizophrenia. Arch. Gen. Psychiatry 67, 1246–1254 (2010).
